The Relationship between Demographic Factors in Adult Patients with Stroke

Samad Shams-Vahdati, Alireza Ala, Eliar Sadeghi-Hokmabad, Neda Parnianfard, Nasim Ahmadi Sepehri, Maedeh Gheybi


Background: Developing countries are challenging with stroke as the third cause of death in developed countries and the most popular neurologic disease which results in disability. This study was designed to assess the relationship between demographic factors and early outcome in adult patients with difference type of stroke. Methods and Materials: A retrospective register review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a neurologist or physician to obtain the clinical diagnosis, patient characteristics. Their demographic data (such as age, gender), NIHSS score and MRS score were filled in questionnaire. the significant variables were verified in a multivariable model to achieve an attuned estimate of effect. Results: A total of 861 patients with stroke were included in the analysis; the male and female sex in the statistical population were 56% and 43%; the mean age of the patients was 14.32 ± 61.74. The mean NIHSS (16.08±10.51) & MRS (3.66) scores were evaluated, respectively 47% severe stroke (NICHSS>16). There was no significant relationship between age increase and NIHSS increase (P = 0.86). Conclusion: Aging has a significant relationship with increased stroke. Gender and age differences in risk of stroke outcomes are mostly described by variations in physical characteristics and stroke severity of the patients.


Gender, Age, Stroke

Full Text:



Reeves MJ, Bushnell CD, Howard G, et al. Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes. Lancet Neurol 2008;7:915–26.

Wang W, Jiang B, Sun H, Ru X, Sun D, Wang L, Wang L, Jiang Y, Li Y, Wang Y, Chen Z. Prevalence, Incidence, and Mortality of Stroke in ChinaClinical Perspective: Results from a Nationwide Population-Based Survey of 480 687 Adults. Circulation. 2017 Feb 21;135(8):759-71.

Phan HT, Blizzard CL, Reeves MJ, Thrift AG, Cadilhac D, Sturm J, Heeley E, Otahal P, Konstantinos V, Anderson C, Parmar P. Sex differences in long-term mortality after stroke in the INSTRUCT (INternational STRoke oUtComes sTudy): a meta-analysis of individual participant data. Circulation: Cardiovascular Quality and Outcomes. 2017 Feb 1;10(2):e003436.

Li L, Geraghty OC, Mehta Z, Rothwell PM, Study OV. Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. The Lancet. 2017 Jul 29;390(10093):490-9.

Gall SL, Tran PL, Martin K, Blizzard L, Srikanth V. Sex differences in long-term outcomes after stroke: functional outcomes, handicap, and quality of life. Stroke 2012;43:1982–7

Brott T, Adams Jr HP, Olinger CP, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20:864–70.

Herdon R. Handbook of neurologic rating scales. New York: Demos Vermande; 1997 .

Appelros P, Stegmayr B, Terent A. Sex differences in stroke epidemiology: a systematic review. Stroke 2009;40:1082–90.

Di Carlo A, Lamassa M, Baldereschi M, et al. Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe: data from a multicenter multinational hospital-based registry. Stroke 2003;34:1114–9.

Lai SM, Duncan PW, Dew P, Keighley J. Sex differences in stroke recovery. Prev Chronic Dis 2005;2:A13.

Li OL, Silver FL, Lichtman J, Fang J, Stamplecoski M, Wengle RS, Kapral MK. Sex differences in the presentation, care, and outcomes of transient ischemic attack: Results from the Ontario stroke registry. Stroke. 2016 Jan;47(1):255-7.

Asdaghi N, Romano JG, Wang K, Ciliberti-Vargas MA, Koch S, Gardener H, Dong C, Rose DZ, Waddy SP, Robichaux M, Garcia EJ. Sex Disparities in Ischemic Stroke Care: FL-PR CReSD Study (Florida–Puerto Rico Collaboration to Reduce Stroke Disparities). Stroke. 2016 Oct 1;47(10):2618-26.

Bray BD, Paley L, Hoffman A, James M, Gompertz P, Wolfe CD, Hemingway H, Rudd AG, SSNAP Collaboration. Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England. The Lancet Public Health. 2018 Apr 1;3(4):e185-93.

Madsen TE, Khoury J, Alwell K, Moomaw CJ, Rademacher E, Flaherty ML, Woo D, Mackey J, La Rosa FD, Martini S, Ferioli S. Sex-specific stroke incidence over time in the Greater Cincinnati/Northern Kentucky Stroke Study. Neurology. 2017 Sep 5;89(10):990-6.

McDermott M, Lisabeth LD, Baek J, Adelman EE, Garcia NM, Case E, Campbell MS, Morgenstern LB, Zahuranec DB. Sex disparity in stroke quality of care in a community-based study. Journal of Stroke and Cerebrovascular Diseases. 2017 Aug 1;26(8):1781-6..

Veerbeek JM, Kwakkel G, van Wegen EE, Ket JC, Heymans MW. Early prediction of outcome of activities of daily living after stroke: a systematic review. Stroke 2011;42:1482–8.



  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

2013-2023 (CC-BY) Australian International Academic Centre PTY.LTD.

Advances in Bioscience and Clinical Medicine