Accuracy of MRI Sequences in Detecting Multiple Sclerosis (MS) Lesions: A Systematic Review

Abdullah Dhaifallah Almutairi, Rozi Mahmud, Subapriya Suppiah, Hasyma Abu Hassan


Introduction: Multiple sclerosis (MS) is one of the chronic autoimmune central nervous system disorder that characterized by demyelination of axon in brain cortex and the other grey and white matter regions and it makes several symptoms. Magnetic Resonance Imaging (MRI) with high sensitivity is the most important preclinical tool for the diagnosis of MS. The aim is to conduct systematic review studies carried out on accuracy of MRI sequences in detecting Multiple Sclerosis (MS) lesions. Methods: This study was systematic review. The related studies accomplished about using MRI in detecting MS lesions in worldwide included by searching in database and journal websites, including PubMed, Google Scholar and Medline. These articles searched by main keywords such as MRI, MS, lesions, sequence, and detecting. Conclusion: Our reviewing study showed that Double Inversion Recovery (DIR) Sequence in MRI has a high sensitivity to detect of lesion of MS. Furthermore, we recommend that the physicians add DIR sequence in routine MR protocols for diagnostic MS in patients.


Magnetic Resonance Imaging, Multiple Sclerosis, Lesions

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