Role of Duplex Ultrasound in Diagnosis of Prostate Cancer and Localization for Biopsy

Iman Yazdaninia, Abolhassan Shakeri Bavil Olyaei, Javad Jalili, Hasan Mohammad Rezaei, Armin Zarrintan

Abstract


Background: Prostate cancer is a common malignancy among men and is one of major problem of health care system. Ultrasonography is useful, safe, and available method for evaluation of prostate problem. The aim of present study was to evaluate the role of duplex ultrasound in diagnosis of prostate cancer and localization for biopsy. Methods & Materials: In a descriptive analytical study, 27 patients with increased level of PSA, who were referred to ultrasonography ward of Imam Reza Hospital for prostate biopsy, were included in the study and examined with color doppler and duplex ultrasonography. Biopsy was done for all patients using transrectal guided ultrasonography. Resistance index (RI), pulsatility index (PI), prostate volume, and pathology findings of biopsy, were evaluated. Results: Among 27 patients, 12 patients (44.4%) had prostate cancer and 15 patients (55.6%) had benign prostatic hyperplasia (BPH). In evaluation of RI & PI in prostate arteries, there were no significant differences between patients with malignancy and patients with BPH (P>0.05). Mean volume of prostate in patient with prostate cancer was 36.56±3.13 ml and in patients with BPH was 54.76±5.42 ml. Mean volume of prostate in patients with BPH was significantly more than patients with prostate cancer (P=0.020). Conclusion: Based on the findings of present study; there is no significant correlation between vascular features of prostate arteries and prostate malignancy, and volume of prostate in patients with BPH was significantly higher than patients with prostate cancer.

Keywords


Duplex Ultrasonography, Prostate Cancer, Transrectal biopsy

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References


Godley, P. A., & Schell, M. J. (1999). Adjusted odds ratios under nondifferential misclassification: application to prostate cancer. Journal of clinical epidemiology, 52(2), 129-136.

Ebrahimi, M. (2004). Prevalence of hormone dependent cancers in Iran during 1986–1997. International Journal of Gynecological Cancer, 14, 204.

Neumaier CE, Martinoli C, Derchi LE, Silvestri E, Rosenberg I. Normal prostate gland: examination with color Doppler US. Radiology 1995; 196:453–457.

Louvar, E., Littrup, P. J., Goldstein, A., Yu, L., Sakr, W., & Grignon, D. (1998). Correlation of color Doppler flow in the prostate with tissue microvascularity. Cancer, 83(1), 135-140.

Rifkin, M. D., Sudakoff, G. S., & Alexander, A. A. (1993). Prostate: techniques, results, and potential applications of color Doppler US scanning. Radiology, 186(2), 509-513.

Rubin, J. M., Bude, R. O., Carson, P. L., Bree, R. L., & Adler, R. S. (1994). Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler US. Radiology, 190(3), 853-856.

Neumaier CE, Martinoli C, Derchi LE, Silvestri E, Rosenberg I. Normal prostate gland: examination with color Doppler US. Radiology 1995; 196:453–457.

Grubb 3rd, R. L., & Kibel, A. S. (2006). Prostate cancer: screening, diagnosis and management in 2007. Missouri medicine, 104(5), 408-13.

Simon, H. B. (2004). On call. My doctor gave me a prescription for Uroxatral to treat my enlarged prostate. I tried to look up this medicine in your Harvard Medical School Guide to Men's Health, but I couldn't find it. What can you tell me about Uroxatral? Harvard men's health watch, 8(11), 7.

Ward, J. F., Slezak, J. M., Blute, M. L., Bergstralh, E. J., & Zincke, H. (2005). Radical prostatectomy for clinically advanced (cT3) prostate cancer since the advent of prostate‐specific antigen testing: 15‐year outcome. BJU international, 95(6), 751-756.

Sadeghi-Nejad H, Simmons M, Dakwar G, Dogra V. Controversies in transrectal ultrasonography and prostate biopsy. Ultrasound Q 2006; 22:169–175.

Shinohara K, Wheeler TM, Scardino PT. The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations. J Urol 1989; 142:76–82.

Coley CM, Barry MJ, Fleming C, Mulley AG. Early detection of prostate cancer, part I: prior probability and effectiveness of tests. The American College of Physicians. Ann Intern Med 1997; 126:394–406.

Raja J, Ramachandran N, Munneke G, Patel U. Current status of transrectal ultrasound-guided prostate biopsy in the diagnosis of prostate cancer. Clin Radiol 2006; 61:142–153.

Bigler SA, Deering RE, Brawer MK. Comparison of microscopic vascularity in benign and malignant prostate tissue. Hum Pathol 1993; 24:220–226.

Siegal JA, Yu E, Brawer MK. Topography of neovascularity in human prostate carcinoma. Cancer 1995; 75:2545–2551.

Kurjak A, Shalan H, Kupesic S, et al. Transvaginal colour Doppler sonography in the assessment of pelvic tumour vascularity. Ultrasound Obstet Gynecol 1993; 3:137–154.

Obwegeser R, Berghammer P, Lorenz K, Auerbach L, Kubista E. Color Doppler sonography of the lateral thoracic (breast-feeding) arteries: a new approach to the diagnosis of breast disease. Ultrasound Obstet Gynecol 2001; 18: 515–519.

Delongchamps NB, Peyromaure M, Dinh-Xuan AT. Role of vascular endothelial growth factor in prostate cancer. Urology 2006; 68:244–248.

Remzi, M., et al. & European Society for Oncological Urology (ESOU. (2004). Can power Doppler enhanced transrectal ultrasound guided biopsy improve prostate cancer detection on first and repeat prostate biopsy?. European urology, 46(4), 451-456.

Al-Azab, R., Toi, A., Lockwood, G., Kulkarni, G. S., & Fleshner, N. (2007). Prostate volume is strongest predictor of cancer diagnosis at transrectal ultrasound-guided prostate biopsy with prostate-specific antigen values between 2.0 and 9.0 ng/mL. Urology, 69(1), 103-107.

Tsuru, N., Kurita, Y., Suzuki, K., & Fujita, K. (2005). Resistance index in benign prostatic hyperplasia using power Doppler imaging and clinical outcomes after transurethral vaporization of the prostate. International journal of urology, 12(3), 264-269.

Zhang, X., et al. (2012). Resistive index of prostate capsular arteries: a newly identified parameter to diagnose and assess bladder outlet obstruction in patients with benign prostatic hyperplasia. The Journal of urology, 188(3), 881-887.

Kojima, M., Ochiai, A., Naya, Y., Okihara, K., Ukimura, O., & Miki, T. (2000). Doppler resistive index in benign prostatic hyperplasia: correlation with ultrasonic appearance of the prostate and infravesical obstruction. European urology, 37(4), 436-442.

Berger AP, Horninger W, Kektic J, et al. Vascular resistance in the prostate evaluated by colour Doppler ultrasonography: is benign prostatic hyperplasia a vascular disease? BJU Int 2006; 98:587–590.

Özdemir H, Onur R, Bozgeyik Z, Orhan I, Ogras MS, Ogur E. Measuring resistance index in patients with BPH and lower urinary tract symptoms. J Clin Ultrasound 2005; 33:176–180.

Tsuru N, Kurita Y, Masuda H, Suzuki K, Fujita K. Role of Doppler ultrasound and resistive index in benign prostatic hypertrophy. Int J Urol 2002; 9:427–430.

Turgut AT, Olcucuoglu E, Kosar P, Geyik PO, Kosar U, Dogra V. Power Doppler ultrasonography of the feeding arteries of the prostate gland: a novel approach to the diagnosis of prostate cancer? J Ultrasound Med. 2007;26(7):875-83.




DOI: https://doi.org/10.7575/aiac.abcmed.v.6n.4p.20

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