Comparison between the Effects of Early and Late Nourishing by Jejunal Feeding in Patients with Esophageal Cancer after Esophagectomy

Samad Beheshti Rouy, Farzad Kakaei, Mehran Rahimi


Background: Esophageal cancer has become one of the most common cancers in the last decade and multiple treatment methods can be prescribe based on its extent and grade. It has been proven that nutritional states are very important to tolerance surgery. Aim: The aim of this study was to evaluate the efficacyand safety of early (6 hours) starting of jejunal feeding comparing with late (72 hours) nourishing by jejunal feeding in patients with esophageal cancer after esophagectomy. Methods: In this prospective-randomized study, 50 patients undergoing esophagectomy for esophageal cancer were randomly divided into two groups. Then patients underwent surgery. In case group (n=25) nourishing by jejunostomy was started 6 hours after surgery and in control group (n=25) as a conventional method, nourishing by jejunostomy was started 72 hours after surgery. Results: There were no significantdifferences between two groups in term of age, type of tumor and grade of tumor. In case and control group; ICU stay time, hospitalization, transfusion rate, preoperative serum albumin level were 2.2±0.32 and 1.76±0.14 days, 9.28±0.56 and 9.12±0.14 days, 0.24±0.11 and 0.28±0.1 unites, 3.93±0.09 and 3.8±0.07, respectively. The albumin serum levels 6 hours and 72 after surgery in case and control group were 3.74±0.07 and 3.6±0.08, 3.66±0.08 and 3.54±0.07, respectively. Conclusion: Based on the results, the transfusion rate, ICU stay and hospitalization days in case group was lower than control group. But there were no significantdifferences between two groups. In general, it seems that early start of nutrition via jejunal tube in patients undergoing esophagectomy have no more complications comparing conventional method. Its benefits nee additional studies.


jejunal Feeding, Early Nourishing, Esophageal Cancer

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