Comparison between the Effects of Early and Late Nourishing by Jejunal Feeding in Patients with Esophageal Cancer after Esophagectomy

Samad Beheshti Rouy, Farzad Kakaei, Mehran Rahimi

Abstract


Background: Esophageal cancer has become one of the most common cancers in the last decade and multiple treatment methods can be prescribe based on its extent and grade. It has been proven that nutritional states are very important to tolerance surgery. Aim: The aim of this study was to evaluate the efficacyand safety of early (6 hours) starting of jejunal feeding comparing with late (72 hours) nourishing by jejunal feeding in patients with esophageal cancer after esophagectomy. Methods: In this prospective-randomized study, 50 patients undergoing esophagectomy for esophageal cancer were randomly divided into two groups. Then patients underwent surgery. In case group (n=25) nourishing by jejunostomy was started 6 hours after surgery and in control group (n=25) as a conventional method, nourishing by jejunostomy was started 72 hours after surgery. Results: There were no significantdifferences between two groups in term of age, type of tumor and grade of tumor. In case and control group; ICU stay time, hospitalization, transfusion rate, preoperative serum albumin level were 2.2±0.32 and 1.76±0.14 days, 9.28±0.56 and 9.12±0.14 days, 0.24±0.11 and 0.28±0.1 unites, 3.93±0.09 and 3.8±0.07, respectively. The albumin serum levels 6 hours and 72 after surgery in case and control group were 3.74±0.07 and 3.6±0.08, 3.66±0.08 and 3.54±0.07, respectively. Conclusion: Based on the results, the transfusion rate, ICU stay and hospitalization days in case group was lower than control group. But there were no significantdifferences between two groups. In general, it seems that early start of nutrition via jejunal tube in patients undergoing esophagectomy have no more complications comparing conventional method. Its benefits nee additional studies.

Keywords


jejunal Feeding, Early Nourishing, Esophageal Cancer

Full Text:

PDF

References


Smink DS. Schwartz's Principles of Surgery. Annals of Surgery. 2015;261(5):1026.

Baba Y, Yoshida N, Shigaki H, Iwatsuki M, Miyamoto Y, Sakamoto Y, et al. Prognostic impact of postoperative complications in 502 patients with surgically resected esophageal squamous cell carcinoma: a retrospective single-institution study. Annals of surgery. 2016;264(2):305-11.

Sharma P, Jain S, Karunanithi S, Pal S, Julka PK, Thulkar S, et al. Diagnostic accuracy of 18F-FDG PET/CT for detection of suspected recurrence in patients with oesophageal carcinoma. European journal of nuclear medicine and molecular imaging. 2014;41(6):1084-92.

Hirahara N, Matsubara T, Hayashi H, Takai K, Nakada S, Tajima Y. Prognostic Importance of Controlling Nutritional Status in Patients Undergoing Curative Thoracoscopic Esophagectomy for Esophageal Cancer. American journal of therapeutics. 2016.

Torre LA, Siegel RL, Ward EM, Jemal A. Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiology and Prevention Biomarkers. 2016;25(1):16-27.

Yoshida N, Harada K, Baba Y, Kosumi K, Iwatsuki M, Kinoshita K, et al. Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer. Langenbeck's archives of surgery. 2017;402(2):333-41.

Tran Chau Quyen, Jongjit Angkatavanich, Tran Van Thuan. Nutrition assessment and its relationship with performance and Glasgow prognostic scores in Vietnamese patients with esophageal cancer. Asia Pac J Clin Nutr 2017;26(1):49-58.

Weijs TJ, Berkelmans GH, Nieuwenhuijzen GA, Ruurda JP, v Hillegersberg R, Soeters PB, et al. Routes for early enteral nutrition after esophagectomy. A systematic review. Clinical Nutrition. 2015;34(1):1-6.

Chow R, Bruera E, Chiu L, Chow S, Chiu N, Lam H, et al. Enteral and parenteral nutrition in cancer patients: a systematic review and meta-analysis. Annals of palliative medicine. 2016;5(1):30-41.

Fujita T, Daiko H, Nishimura M. Early enteral nutrition reduces the rate of life-threatening complications after thoracic esophagectomy in patients with esophageal cancer. European surgical research. 2012;48(2):79-84.

Yao F, Wang J, Yao J, Hang F, Cao S, Qian J, et al. Early Chest Tube Removal After Thoracoscopic Esophagectomy with High Output. Journal of Laparoendoscopic & Advanced Surgical Techniques. 2016;26(1):17-22.

Goldman L, Schafer AI. Goldman's Cecil Medicine E-Book: Elsevier Health Sciences; 2011.

Lim JH, Ju DL, Hwang Y, Kang CH. Early postoperative 24-hour continuous jejunostomy feeding in esophagectomy patients. Clinical nutrition research. 2014;3(1):69-73.

Kobayashi K, Koyama Y, Kosugi S-i, Ishikawa T, Sakamoto K, Ichikawa H, et al. Is early enteral nutrition better for postoperative course in esophageal cancer patients? Nutrients. 2013;5(9):3461-9.

Gabor S, Renner H, Matzi V, Ratzenhofer B, Lindenmann J, Sankin O, et al. Early enteral feeding compared with parenteral nutrition after oesophageal or oesophagogastric resection and reconstruction. British journal of nutrition. 2005;93(4):509-13.

Manba N, Koyama Y, Kosugi S-i, Ishikawa T, Ichikawa H, Minagawa M, et al. Is early enteral nutrition initiated within 24 hours better for the postoperative course in esophageal cancer surgery? Journal of clinical medicine research. 2014;6(1):53.

Wheble GA, Benson RA, Khan OA. Is routine postoperative enteral feeding after oesophagectomy worthwhile? Interactive cardiovascular and thoracic surgery. 2012;15(4):709-12.




DOI: http://dx.doi.org/10.7575/aiac.abcmed.v.6n.1p.30

Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

2013-2019 (CC-BY) Australian International Academic Centre PTY.LTD.

Advances in Bioscience and Clinical Medicine