A case of chronic necrotizing bronchopulmonary aspergillosis presenting with hemoptysis and a pulmonary mass mimicking lung cancer

Servet Kayhan, Ünal Şahin, Yıldıray Bekar, Halit Çınarka, Aziz Gümüş, Recep Bedir

Abstract


Chronic necrotizing pulmonary aspergillosis usually affects the immunocompromised patients with abnormal pulmonary defense mechanisms. Herein, we report a 62-year-old man admitted to our clinic with the complaint of chronic productive cough, hemoptysis and history of recurrent lower respiratory tract infections in last one year. Computed tomographic scan revealed an irregularly shaped mass in the right middle lobe. Fiberoptic bronhoscopy demonstrated the hemorrhage and stenosis in the middle lobe bronchus. Cytologic examinations of bronchoscopic samples demonstrated the hyphae of Aspergillus. An urgent thoracotomy, right middle lobectomy and sleeve resection of posterior segment of upper lobe were performed due to massive hemoptysis and the final diagnosis was local invasive and necrotizing aspergillosis.

 

Keywords: Bronchopulmonary; Aspergillosis; Hemoptysis


Full Text:

PDF

References


Sokouti M, Golzari SE, Aghdam BA. Surgery of uncomplicated pulmonary hydatid cysts: capitonnage or uncapitonnage? Int J Surg 2011; 9(3):221-4.

Sokouti M. Golzari S. A giant bulla of the lung mimicking tension pnemothorax (a case report). Journal of Cardiovascular and Thoracic Research 2010;2(2):41-44.

Sokouti M, Halimi M, Golzari SE. Squamous cell carcinoma on the remaining sequel of tuberculosis, presented as pancoast tumor 8 years later. Tanaffos 2012;11(3):49-51.

Kayhan S, Cinarka H, Gumus A, Sahin U. Pneumonia and Pandemic Influenza A H1N1 Virus Infection: A Review of the Literature. ABC med. 2014;2(1):3-14. doi.10/7575/aiac/abcmed/v/2n/1 p/2

Golzari SE, Sokouti M, Ghaffari A, Bazzazi AM, Ghabili K. Ultrasonography in diagnosis of pulmonary hydatid cysts. Lancet Infect Dis. 2013;13(4):294.

Sokouti M, Pezeshkian M, Ghabili K, Golzari SE. Surgical Procedures and Postoperative Complications in Patients with Giant and Non-giant Pulmonary Hydatid Cysts. Life Sci J 2013;10(1): 138- 142.

Feizi I, Sokouti M, Golzari SE, Gojazadeh M, Farahnak MR, Hashemzadeh S, Rahimi-Rad MH. Determination of safe margin in the surgical pathologic specimens of non-small cell carcinoma of the lung. Pneumologia 2013;62(1):16-18.

Sokouti M, Golzari SE, Kayhan S, Sabermarouf B. Recurrence Following Pulmonary Hydatid Disease Surgery. World J Surg. 2013 Jul 10.

Nejadkazem M, Hemati A, Vegari S, Adibpour M, Davarimajd L. Fungal Agents as a Cause of Nasal Polyposis. ABC med. 2014. (In press)

Nam HS, Jeon K, Um SW, Suh GY, Chung MP, Kim H, Kwon OJ, Koh WJ. Clinical characteristics and treatment outcomes of chronic necrotizing pulmonary aspergillosis: a review of 43 cases. Int J Infect Dis. 2010;14(6):e479-82.

Saraceno JL, Phelps DT, Ferro TJ, Futerfas R, Schwartz DB. Chronic necrotizing pulmonary aspergillosis: approach to management. Chest 1997;112:541–8.

Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2008;46:327–60.

Binder RE, Faling LJ, Pugatch RD, Mahasaen C, Snider GL. Chronic necrotizing pulmonary aspergillosis: a discrete clinical entity. Medicine (Baltimore) 1982;61:109–24.

Dupont B. Itraconazole therapy in aspergillosis: study in 49 patients. J Am Acad Dermatol 1990;23:607–14.

De Beule K, De Doncker P, Cauwenbergh G, Koster M, Legendre R, Blatchford N, et al. The treatment of aspergillosis and aspergilloma with itraconazole, clinical results of an open international study (1982–1987). Mycoses 1988;31:476–85.

Caras WE, Pluss JL. Chronic necrotizing pulmonary aspergillosis: pathologic outcome after itraconazole therapy. Mayo Clin Proc 1996;71:25–30.

Gefter WB, Weingrad TR, Epstein DM, Ochs RH, Miller WT. ‘Semi-invasive’ pulmonary aspergillosis: a new look at the spectrum of Aspergillus infections of the lung. Radiology 1981;140:313–21.

Binder RE, Faling LJ, Pugatch RD, Mahasaen C, Snider GL. Chronic necrotizing pulmonary aspergillosis: a discrete clinical entity. Medicine (Baltimore) 1982;61:109–24.

Zmeili OS, Soubani AO. Pulmonary aspergillosis: a clinical update. QJM 2007;100:317–34.

Denning DW, Riniotis K, Dobrashian R, Sambatakou H. Chronic cavitary and fibrosing pulmonary and pleural aspergillosis: case series, proposed nomenclature change, and review. Clin Infect Dis 2003;37(Suppl 3):S265–80.

Hedayati MT, Mayahi S, Movahedi M, Shokohi T. A Study on Fungal Flora of Tap Water as a Potential Reservoir of Fungi in Hospitals from Sari city, Iran. J Mycol Méd 2011; 21: 10–14.

Meersseman W, Vandecasteele SJ, Wilmer A, Verbeken E, Peetermans WE, Van Wijngaerden E. Invasive aspergillosis in critically ill patients without malignancy. Am J Respir Crit Care Med 2004; 170: 621–625.

Hedayati MT, Khodavaisy S, Alialy M, Omran SM, Habibi MR. Invasive aspergillosis in intensive care unit patients in Iran. Acta Medica (Hradec Kralove). 2013;56(2):52-6.

Takeuchi Y, Shirai T, Sakurai S, Mikamo M, Fujii M, Suda T. Allergic bronchopulmonary aspergillosis presenting with a pulmonary mass mimicking lung cancer. Respirology Case Reports 2013; 1(1): 5–7

Yasuda M, Nagashima A, Haro A, Saitoh G. Aspergilloma mimicking a lung cancer. Int J Surg Case Rep. 2013;4(8):690-2. doi: 10.1016/j.ijscr.2013.02.028.

Jung SW, Kim MW, Cho SK, Kim HU, Lee DC, Yoon BK, Jeong JP, Ko YC. A Case of Endobronchial Aspergilloma Associated with Foreign Body in Immunocompetent Patient without Underlying Lung Disease. Tuberc Respir Dis (Seoul).2013May;74(5):231-4.


Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

2013-2023 (CC-BY) Australian International Academic Centre PTY.LTD.

Advances in Bioscience and Clinical Medicine