A Giant Sacrococcygeal Chordoma: Case Report and Literature Review

Xiang Yang, Seidu A. Richard, Wei Zhao, Jiagang Liu, Siqing Huang

Abstract


Introduction: Chordomas are rare low-grade malignant lesions that are mostly seen in the spine. They constitute about 1% of intracranial tumors and 3-4% of all primary bone tumors. The principal spinal location is usually the sacrococcygeal and infrequently the sphenooccipital and cervical areas. Case Presentation: We present a 74-year-old man with a huge sacrococcygeal mass extending to both buttocks. Computerized tomography (CT-scan) and magnetic resonance imaging (MRI) as well as computerized tomographic angiography (CTA) evaluations were suggestive to chordoma. Immunohistochemical analysis confirmed the diagnosis after the patient was successfully operated on. All aggravating symptoms resolved after the operation. Conclusion: The management of giant sacrococcygeal chordomas can be very challenging but with all-inclusive treatment, complete cure is achievable although recurrence can occur. In our case, surgery alone was curative. Preoperative CTA aided us in achieving total tumor resection.

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References


Wang F, Bai J, Wu Y, Zhang Y. Multiple distant metastases of a sacrococcygeal chordoma. Neurosurgery Quarterly. 2013;23(3):210-2.

Akyol M, Varol U, Yildiz I, Bayoglu IV, Yildiz Y, Demir L, et al. Isolated liver metastasis of sacrococcygeal chordoma: case report and review of the literature. Case reports in oncological medicine. 2014;2014.

McMaster ML, Goldstein AM, Bromley CM, Ishibe N, Parry DM. Chordoma: incidence and survival patterns in the United States, 1973–1995. Cancer Causes & Control. 2001;12(1):1-11.

Atalar H, Selek H, Yıldız Y, Sağlık Y. Management of sacrococcygeal chordomas. International orthopaedics. 2006;30(6):514-8.

Rich TA, Schiller A, Suit HD, Mankin HJ. Clinical and pathologic review of 48 cases of chordoma. Cancer. 1985;56(1):182-7.

York JE, Kaczaraj A, Abi-Said D, Fuller GN, Skibber JM, Janjan NA, et al. Sacral chordoma: 40-year experience at a major cancer center. Neurosurgery. 1999;44(1):74-9.

Delank K-S, Kriegsmann J, Drees P, Eckardt A, Eysel P. Metastasizing chordoma of the lumbar spine. European Spine Journal. 2002;11(2):167-71.

MURPBEY M. Primary tumors of the spine: Ridiologic-pathologic correlations. Radiographics. 1996;15:1131-58.

Launay SG, Chetaille B, Medina F, Perrot D, Nazarian S, Guiramand J, et al. Efficacy of epidermal growth factor receptor targeting in advanced chordoma: case report and literature review. BMC cancer. 2011;11(1):423.

Sung MS, Lee GK, Kang HS, Kwon ST, Park JG, Suh JS, et al. Sacrococcygeal chordoma: MR imaging in 30 patients. Skeletal radiology. 2005;34(2):87-94.

Rosenthal D, Scott J, Mankin H, Wismer G, Brady T. Sacrococcygeal chordoma: magnetic resonance imaging and computed tomography. American journal of roentgenology. 1985;145(1):143-7.

Meyers SP, Hirsch W, Curtin HD, Barnes L, Sekhar LN, Sen C. Chordomas of the skull base: MR features. American journal of neuroradiology. 1992;13(6):1627-36.

Stacchiotti S, Casali PG, Vullo SL, Mariani L, Palassini E, Mercuri M, et al. Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers. Annals of surgical oncology. 2010;17(1):211-9.

Saxton JP. Chordoma. International Journal of Radiation Oncology• Biology• Physics. 1981;7(7):913-5.

Fleming GF, Heimann PS, Stephens JK, Simon MA, Ferguson MK, Benjamin RS, et al. Dedifferentiated chordoma: response to aggressive chemotherapy in two cases. Cancer. 1993;72(3):714-8.

Guiu S, Guiu B, Feutray S, Chauffert B. Direct intratumoral chemotherapy with carboplatin and epinephrine in a recurrent cervical chordoma: case report. Neurosurgery. 2009;65(3):E629-E30.

Hindi N, Casali PG, Morosi C, Messina A, Palassini E, Pilotti S, et al. Imatinib in advanced chordoma: a retrospective case series analysis. European journal of cancer. 2015;51(17):2609-14.

Collins GR, Essary L, Strauss J, Hino P, Cockerell CJ. Incidentally discovered distant cutaneous metastasis of sacral chordoma: a case with variation in S100 protein expression (compared to the primary tumor) and review of the literature. Journal of cutaneous pathology. 2012;39(6):637-43.




DOI: https://doi.org/10.7575/aiac.abcmed.v.7n.2p.60

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